4) What is the most significant difference between a retroviral vector and an adenoviral vector, when they are used for gene therapy in humans?a) if you use a retroviral vector, the ‘good’ gene being used for gene therapy will not be integrated into the host genome, reducing the risk of insertion into a bad locationb) adenoviruses can infect human cells, but retroviruses cannot, so retroviral vectors are saferc) retroviruses can infect human cells, but adenoviruses cannot, so adenoviral vectors are saferd) if you use an adenoviral vector, the ‘good’ gene being used for gene therapy will not be integrated into the host genome, reducing the risk of insertion into a bad location5) Which of these best describes somatic cell nuclear transfer?a) reprogramming an adult somatic cell nucleus to behave like an embryonic cell nucleus by placing it in an enucleated eggb) causing embryonic stem cells to differentiate into a differentiated cell type by adding growth factors or other molecules to them in tissue culturec) reprogramming an adult somatic cell nucleus to behave like an embryonic cell nucleus by introducing several transcription factors into itd) using retroviral or adenoviral vectors to introduce a normal copy of a gene into mutant cellse) transferring a gene from one species into another6) In an automated machine that performs dideoxy sequencing and capillary electrophoresis of fluroescently-labelled DNA molecules, which of the following DNA fragments would run out of the bottom of the capillary first?a) ATb) ATCCc) ATCCCGd) ATCCCGATTGCACGTTe) ATCCCGAT
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